One Pot Synthesis of Alpha-Aminonitrile and Alpha-Amino Acid From Schiff Bases

Addition of Potassium cyanide to a mixture of Schiff base and lithium perchlorate afforded a-aminonitriles in high yields. Addition of potassium cyanide to a methanolic solution of Schiff base and phosphoric acid afforded a-aminonitriles. When the reaction mixture was refluxed it gave a-amino acids...

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Veröffentlicht in:Iranian journal of chemistry & chemical engineering 1999-01, Vol.18 (1), p.33-35
Hauptverfasser: Mohammad M. Hashemi, Behnaz Almasi
Format: Artikel
Sprache:eng
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Zusammenfassung:Addition of Potassium cyanide to a mixture of Schiff base and lithium perchlorate afforded a-aminonitriles in high yields. Addition of potassium cyanide to a methanolic solution of Schiff base and phosphoric acid afforded a-aminonitriles. When the reaction mixture was refluxed it gave a-amino acids in high yields.
ISSN:1021-9986
1021-9986