Transformation gap from research findings to large-scale commercialized products in microfluidic field

The field of microfluidics has experienced rapid growth in the last several decades, yet it isn't considered to be a large industry comparable to semiconductor and consumer electronics. In this review, we analyzed the entire process of the transformation from research findings to commercialized products in microfluidics, as well as the significant gap during the whole developing process between microchip fabrication in R&D and large-scale production in the industry. We elaborated in detail on various materials in the microfluidics industry, including silicon, glass, PDMS, and thermoplastics, discussing their characteristics, production processes, and existing products. Despite challenges hindering the large-scale commercialization of microfluidic chips, ongoing advancements and applications are expected to integrate microfluidic technology into everyday life, transforming it into a commercially viable field with substantial potential and promising prospects. [Display omitted] •Discussion of the significant transformation gap from R&D to commercialization in microfluidic field.•Detailed overview of various materials utilized in microfluidic industry.•Presentation of representative examples of commercialized products in microfluidic industry.