Prognostic effect of high-density lipoprotein cholesterol level in patients with atherosclerotic cardiovascular disease under statin treatment

In patients with atherosclerotic cardiovascular disease (ASCVD) under statin treatment, the influence of on-treatment level of high-density lipoprotein cholesterol (HDL-C) on cardiovascular (CV) events is controversial. Statin-treated patients were selected from the Taiwanese Secondary Prevention fo...

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Veröffentlicht in:	Scientific reports 2020-12, Vol.10 (1), p.21835-21835, Article 21835
Hauptverfasser:	Li, Yi-Heng, Tseng, Wei-Kung, Yin, Wei-Hsian, Lin, Fang-Ju, Wu, Yen-Wen, Hsieh, I-Chang, Lin, Tsung-Hsien, Sheu, Wayne Huey-Herng, Yeh, Hung-I, Chen, Jaw-Wen, Wu, Chau-Chung
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4019 692/499 Aged Arteriosclerosis Atherosclerosis Body weight Cardiovascular disease Cardiovascular diseases Cerebral infarction Cholesterol Cholesterol, HDL - blood Coronary Artery Disease - blood Coronary Artery Disease - diagnosis Coronary Artery Disease - drug therapy Coronary Artery Disease - epidemiology Diabetes mellitus Female Follow-Up Studies High density lipoprotein Humanities and Social Sciences Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage Male Middle Aged multidisciplinary Myocardial infarction Myocardial Infarction - blood Myocardial Infarction - diagnosis Myocardial Infarction - drug therapy Myocardial Infarction - epidemiology Prognosis Prospective Studies Registries Risk Factors Science Science (multidisciplinary) Statins Stroke - blood Stroke - diagnosis Stroke - drug therapy Stroke - epidemiology
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Zusammenfassung:	In patients with atherosclerotic cardiovascular disease (ASCVD) under statin treatment, the influence of on-treatment level of high-density lipoprotein cholesterol (HDL-C) on cardiovascular (CV) events is controversial. Statin-treated patients were selected from the Taiwanese Secondary Prevention for patients with AtheRosCLErotic disease (T-SPARCLE) Registry, a multicenter, observational study of adult patients with ASCVD in Taiwan. Low HDL-C was defined as
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-020-78828-8