Co‐diagnoses of acute myeloid leukaemia and COVID‐19: presentation and management implications

We report a case of concurrent new diagnoses of confirmed severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and acute myeloid leukaemia (AML). We review the existing literature on coronavirus disease 2019 (COVID‐19) in the immunocompromised patient and the implications for manag...

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Veröffentlicht in:Respirology case reports 2020-10, Vol.8 (7), p.e00650-n/a
Hauptverfasser: O'Brien, Amy, Campling, James, Goodman, Hugh, Chang, Catherina L.
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Sprache:eng
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Zusammenfassung:We report a case of concurrent new diagnoses of confirmed severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and acute myeloid leukaemia (AML). We review the existing literature on coronavirus disease 2019 (COVID‐19) in the immunocompromised patient and the implications for managing our patient's haematological neoplasm. The implications of severe immunocompromise are unclear in the context of infection with SARS‐CoV‐2. Respiratory and viral systemic symptoms remained mild in this patient and this is consistent with the existing literature on COVID‐19 in immunocompromised patients. To our knowledge, this is the first description of a case of SARS‐CoV‐2 infection with AML. We report a case of concurrent new diagnoses of confirmed severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and acute myeloid leukaemia (AML). The implications of severe immunocompromise are unclear in the context of infection with SARS‐CoV‐2. We describe the clinical course of coronavirus disease 2019 (COVID‐19) in this case, review the existing literature on SARS‐CoV‐2 in the immunocompromised patient, and finally the implications for managing her haematological neoplasm.
ISSN:2051-3380
2051-3380
DOI:10.1002/rcr2.650