Shedding Light on the Hidden Benefit of Porphyridium cruentum Culture

Microalgae can represent a reliable source of natural compounds with different activities. Here, we evaluated the antioxidant and anti-inflammatory activity of sulfated exopolysaccharides (s-EPSs) and phycoerythrin (PE), two molecules naturally produced by the red marine microalga (CCALA415). and ce...

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Veröffentlicht in:Antioxidants 2023-01, Vol.12 (2), p.337
Hauptverfasser: Liberti, Davide, Imbimbo, Paola, Giustino, Enrica, D'Elia, Luigi, Silva, Mélanie, Barreira, Luísa, Monti, Daria Maria
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Sprache:eng
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Zusammenfassung:Microalgae can represent a reliable source of natural compounds with different activities. Here, we evaluated the antioxidant and anti-inflammatory activity of sulfated exopolysaccharides (s-EPSs) and phycoerythrin (PE), two molecules naturally produced by the red marine microalga (CCALA415). and cell-based assays were performed to assess the biological activities of these compounds. The s-EPSs, owing to the presence of sulfate groups, showed biocompatibility on immortalized eukaryotic cell lines and a high antioxidant activity on cell-based systems. PE showed powerful antioxidant activity both and on cell-based systems, but purification is mandatory for its safe use. Finally, both molecules showed anti-inflammatory activity comparable to that of ibuprofen and helped tissue regeneration. Thus, the isolated molecules from microalgae represent an excellent source of antioxidants to be used in different fields.
ISSN:2076-3921
2076-3921
DOI:10.3390/antiox12020337