Anti-Nosemosis Activity of Aster scaber and Artemisia dubia Aqueous Extracts

In our previous study, we demonstrated that the ethanol extracts of ( ) and ( ) have anti-nosemosis activity. In our present study, we intend to establish the anti-nosemosis activity of aqueous, ethyl acetate (EA), and butanol (BuOH) extracts of and . In order to determine the optimal dose, we performed both and toxicity for all the extracts and also carried out anti-nosemosis experiments. Although all of the extracts (aqueous, EA, and BuOH) showed and anti-nosemosis activity in a dose-dependent manner, the aqueous extracts of and showed more potent anti-nosemosis activity than the EA and BuOH extracts. Moreover, an aqueous extract of + demonstrated stronger anti-nosemosis activity compared with the aqueous extracts of either or alone. Although the main ingredients in and remain unclear, our results suggest that the active components of and could dissolve in the aqueous fraction.