Relationship of Circulating Endothelial Cells With Obesity and Cardiometabolic Risk Factors in Children and Adolescents

Relationship of Circulating Endothelial Cells With Obesity and Cardiometabolic Risk Factors in Children and Adolescents

Background Circulating endothelial cells (CECs) reflect early changes in endothelial health; however, the degree to which CEC number and activation is related to adiposity and cardiovascular risk factors in youth is not well described. Methods and Results Youth in this study (N=271; aged 8-20 years)...

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Veröffentlicht in:Journal of the American Heart Association 2021-01, Vol.10 (1), p.e018092
Hauptverfasser: Soltero, Erica G, Solovey, Anna N, Hebbel, Robert P, Palzer, Elise F, Ryder, Justin R, Shaibi, Gabriel Q, Olson, Micah, Fox, Claudia K, Rudser, Kyle D, Dengel, Donald R, Evanoff, Nicholas G, Kelly, Aaron S
Format: Artikel
Sprache:eng
Schlagworte:
Adiposity - physiology
Adolescent
adolescents
Age of Onset
Atherosclerosis - blood
Atherosclerosis - diagnosis
Atherosclerosis - physiopathology
Biomarkers - blood
Body Mass Index
Cardiometabolic Risk Factors
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - metabolism
Cardiovascular Diseases - prevention & control
cardiovascular risk
Child
children
Correlation of Data
Endothelial Cells - metabolism
endothelial health
Female
Humans
Immunohistochemistry
Intra-Abdominal Fat - metabolism
Male
novel biomarkers
obesity
Obesity - blood
Obesity - diagnosis
Original Research
United States - epidemiology
Vascular Cell Adhesion Molecule-1 - blood
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Zusammenfassung:Background Circulating endothelial cells (CECs) reflect early changes in endothelial health; however, the degree to which CEC number and activation is related to adiposity and cardiovascular risk factors in youth is not well described. Methods and Results Youth in this study (N=271; aged 8-20 years) were classified into normal weight (body mass index [BMI] percentage
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.120.018092