Evaluation of Osteoblastic Differentiation Induced by Microtextured Titanium Surface Produced by Laser Metal Fusion 3D Printing

In this study, we hypothesized that microtextured titanium (Ti) surfaces produced by laser metal fusion (LMF) 3D printing may play an important role in osteoblastic differentiation of mesenchymal stem cells (MSCs). For that, MSCs derived from mouse bone marrow were cultured on Ti discs produced in t...

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Veröffentlicht in:	Materials research (São Carlos, São Paulo, Brazil) São Paulo, Brazil), 2024-01, Vol.27
Hauptverfasser:	Lopes, Helena Bacha, Rios, Thiago Leonardo, Adolpho, Letícia Faustino, Souza, Alann Thaffarell Portilho de, Lopes, Ulisses Moreira de Andrade, Backes, Eduardo Henrique, Pessan, Luiz Antonio, Freitas, Gileade Pereira
Format:	Artikel
Sprache:	eng
Schlagworte:	3D printing acid etched dental implant surface ENGINEERING, CHEMICAL laser metal fusion MATERIALS SCIENCE, MULTIDISCIPLINARY METALLURGY & METALLURGICAL ENGINEERING osteoblastic differentiation Titanium
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Zusammenfassung:	In this study, we hypothesized that microtextured titanium (Ti) surfaces produced by laser metal fusion (LMF) 3D printing may play an important role in osteoblastic differentiation of mesenchymal stem cells (MSCs). For that, MSCs derived from mouse bone marrow were cultured on Ti discs produced in two different ways: microtextured produced by acid etched (Ti-Ac, control group) and microtextured produced by LMF 3D printing (Ti-3D-LMF, test group), in which it was evaluated: (1) cell proliferation, (2) alkaline phosphatase activity and (3) extracellular matrix mineralization. The results showed that both groups allowed cell proliferation over time (p
ISSN:	1516-1439 1980-5373 1980-5373
DOI:	10.1590/1980-5373-mr-2023-0448