INFLUENCE OF SPLENIC IMPLANTS IN THE SUBCUTANEOUS TISSUE ON ASPLENIC ANIMALS SURVIVAL

The best site for splenic implant was not defined, mainly evaluating the functionality of the implant. To evaluate the effects of autogenous splenic implantation on the subcutaneous tissue in the survival of splenectomized rats. Twenty-one randomly assigned rats were studied in three groups (n=7): group 1 - manipulation of the abdominal cavity and preservation of the spleen; group 2 - total splenectomy; group 3 - splenectomy and implant of the tissue removed in the subcutaneous. The animals were followed for 90 days postoperatively. There was a higher mortality in groups 2 (p=0.0072) and 3 (p=0.0172) in relation to group 1. There was no difference between groups 2 and 3 (p=0.9817). The splenic implant in the subcutaneous is ineffective in the survival of rats submitted to splenectomy.