Computed Tomography Angiography Characteristics of Thin-Cap Fibroatheroma in Patients With Diabetes

It was recently reported that thin-cap fibroatheroma (TCFA) detected by optical coherence tomography was an independent predictor of future cardiac events in patients with diabetes. However, the clinical usefulness of this finding is limited by the invasive nature of optical coherence tomography. Co...

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Veröffentlicht in:	Journal of the American Heart Association 2024-05, Vol.13 (10), p.e033639-e033639
Hauptverfasser:	Suzuki, Keishi, Kinoshita, Daisuke, Niida, Takayuki, Yuki, Haruhito, Fujimoto, Daichi, Dey, Damini, Lee, Hang, McNulty, Iris, Takano, Masamichi, Mizuno, Kyoichi, Ferencik, Maros, Kakuta, Tsunekazu, Jang, Ik-Kyung
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Computed Tomography Angiography - methods Coronary Angiography - methods Coronary Artery Disease - diagnostic imaging Coronary Vessels - diagnostic imaging Coronary Vessels - pathology diabetes Diabetes Mellitus - epidemiology Female Fibrosis high‐risk plaque Humans Male Middle Aged Original Research plaque volume Plaque, Atherosclerotic - diagnostic imaging Predictive Value of Tests Retrospective Studies thin‐cap fibroatheroma Tomography, Optical Coherence - methods Vascular Calcification - diagnostic imaging Vascular Remodeling
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Zusammenfassung:	It was recently reported that thin-cap fibroatheroma (TCFA) detected by optical coherence tomography was an independent predictor of future cardiac events in patients with diabetes. However, the clinical usefulness of this finding is limited by the invasive nature of optical coherence tomography. Computed tomography angiography (CTA) characteristics of TCFA have not been systematically studied. The aim of this study was to investigate CTA characteristics of TCFA in patients with diabetes. Patients with diabetes who underwent preintervention CTA and optical coherence tomography were included. Qualitative and quantitative analyses were performed for plaques on CTA. TCFA was assessed by optical coherence tomography. Among 366 plaques in 145 patients with diabetes, 111 plaques had TCFA. The prevalence of positive remodeling (74.8% versus 50.6%,
ISSN:	2047-9980 2047-9980
DOI:	10.1161/JAHA.123.033639