CD4+CD25+ T regulatory cells in renal transplantation

CD4+CD25+ T regulatory cells in renal transplantation

The immune response to an allograft activates lymphocytes with the capacity to cause rejection. Activation of CD4 + CD25 + Foxp3 + T regulatory cells (Treg) can down-regulate allograft rejection and can induce immune tolerance to the allograft. Treg represent

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Veröffentlicht in:Frontiers in immunology 2022-11, Vol.13, p.1017683-1017683
Hauptverfasser: Cheung, Jason, Zahorowska, Beata, Suranyi, Michael, Wong, Jeffrey K. W., Diep, Jason, Spicer, Stephen T., Verma, Nirupama D., Hodgkinson, Suzanne J., Hall, Bruce M.
Format: Artikel
Sprache:eng
Schlagworte:
Immunology
kidney transplantation
regulatory T cell
transplant tolerance
transplantation
Treg
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Zusammenfassung:The immune response to an allograft activates lymphocytes with the capacity to cause rejection. Activation of CD4 + CD25 + Foxp3 + T regulatory cells (Treg) can down-regulate allograft rejection and can induce immune tolerance to the allograft. Treg represent
ISSN:1664-3224
1664-3224
DOI:10.3389/fimmu.2022.1017683