Association of Serum Ferritin Levels with Haematological Parameters in Thalassaemia Major Patients

Background: To study the association of serum ferritin levels with haematological parameters in thalassaemia major patients. Methods: A total of 135 patients of thalassemia major were selected for this descriptive, cross sectional study. Patients were divided into three groups. Group I consisted of patients with ferritin levels 5000 ng/ml. After taking patient history, complete blood count analysis and serum ferritin level determination was performed. Results: The mean ferritin level of study group was 6062.61 + 3641.796 ng/ml. Most of our patients were receiving less than optimal level of chelation therapy. The number of red cells and platelets in patients with ferritin levels >5000ng/ml were found to be significantly lower ((p=0.0262, and 0.0265 respectively), when compared with patients having ferritin levels