CORRELATIONS BETWEEN ATOPIC DERMATITIS AND THE DANGER OF STOMACH CANCER

Background/ Aim of study: Epidemiological and clinical evidence suggest that allergies might be linked to lowered susceptibility to various cancers. Nevertheless, the exploration of connections between allergies and gastric cancer remains limited in existing research. This study was undertaken to investigate the potential of examining a comprehensive dataset from a population-based perspective, the study investigated potential links between allergies and gastric cancer. Method: Carried out at a tertiary care center in Patna for one year, this cross-sectional study encompassed 500 participants. It focused on analyzing the potential connections between allergies and gastric cancer, taking into account variables such as age, gender, body mass index, smoking habits, and alcohol consumption to address confounding factors. Results: Adjusted for potential confounders, the results of multivariable logistic regression analyses indicated a tendency for a lower risk of gastric cancer among individuals with a history of allergic diseases. However, it’s important to note that these findings did not reach statistical significance. Furthermore, when considering gender-specific associations, the multivariable analysis indicated that a history of atopic dermatitis was linked to a decreased risk of gastric cancer in men. Conclusion: The study’s findings imply that there might be a connection between allergies and a lower risk of gastric cancer, although this association lacks statistical significance. Moreover, the results indicate that atopic dermatitis, specifically in men, is linked to a decreased risk of gastric cancer. Recommendation. It is recommended that researchers referring to this article further evaluate an intensive study on gender-based effects of atopic dermatitis and its correlation with the development of gastric cancer.