Antibody-Secreting Cells To Diagnose Mycobacterium tuberculosis Infection in Children in Pakistan

Antibody-Secreting Cells To Diagnose Mycobacterium tuberculosis Infection in Children in Pakistan

Reliance on microbiologic methods to diagnose infection is a suboptimal approach for children due in part to the paucibacillary nature of the disease. A blood-based biomarker assay, such as the mycobacterial-antibody-secreting cell (MASC) assay, could be a major advance for the field of study of ped...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:mSphere 2020-02, Vol.5 (1)
Hauptverfasser: Iqbal, Najeeha Talat, Ahmed, Kumail, Qamar, Farah N, Shaheen, Fariha, Mehnaz, Aisha, Arif, Fehmina, Saeed, Amna Afzal, Yousuf, Aneeq Muhammad, Raza, Syeda Fatima, Sultana, Shazia, Qureshi, Shahida Mumtaz, Siddiqi, Shakil Ahmad, Houpt, Eric, Thomas, Tania
Format: Artikel
Sprache:eng
Schlagworte:
Age
antibody-secreting cells
Antigens
Biomarkers
C-reactive protein
Cell culture
Children
Clinical Science and Epidemiology
Diagnosis
Ferritin
Immunoglobulins
Inflammation
Lymphocytes B
Malnutrition
Mycobacterium tuberculosis
Optical density
Pediatrics
Tuberculosis
Vaccines
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Reliance on microbiologic methods to diagnose infection is a suboptimal approach for children due in part to the paucibacillary nature of the disease. A blood-based biomarker assay, such as the mycobacterial-antibody-secreting cell (MASC) assay, could be a major advance for the field of study of pediatric tuberculosis (TB). Children
ISSN:2379-5042
2379-5042
DOI:10.1128/mSphere.00632-19