Possible effects of left pulmonary artery stenting in single ventricle patients on bronchial area, lung volume and lung function

Left pulmonary artery (LPA) stenting is often required in single ventricle (SV) patients. Due to their close anatomical relationship an LPA stent could potentially compress the left main bronchus (LMB). We assessed the impact of LPA stenting on bronchial size, pulmonary volumes, and lung function in...

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Veröffentlicht in:Frontiers in pediatrics 2024-01, Vol.11, p.1337568
Hauptverfasser: Callegari, Alessia, Geiger, Julia, Callaghan, Fraser Maurice, Kellenberger, Christian, Usemann, Jakob, Burkhardt, Barbara Elisabeth Ursula, Kretschmar, Oliver, Valsangiacomo Büchel, Emanuela
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Sprache:eng
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Zusammenfassung:Left pulmonary artery (LPA) stenting is often required in single ventricle (SV) patients. Due to their close anatomical relationship an LPA stent could potentially compress the left main bronchus (LMB). We assessed the impact of LPA stenting on bronchial size, pulmonary volumes, and lung function in a cohort of SV patients. Forty-nine patients underwent cardiovascular magnetic resonance (CMR) and 36 spirometry 11 (8-15) years after Fontan. All patients were free of respiratory symptoms. LPA stents were inserted in 17 (35%) patients at 8.8 (3.4-12.6) years. Area/shape of the main bronchi (  = 46) and lung volumes (  = 47) were calculated from CMR-ZTE images for each lung and transformed in right-to-left (r/l) ratio and indexed for BSA. The effect of early stent insertion (prior to stage III) was analyzed. Patients with LPA stent had larger r/l ratio for main bronchus area (  
ISSN:2296-2360
2296-2360
DOI:10.3389/fped.2023.1337568