Genomic Features of Salmonella enterica Subspecies houtenae Serotype 45:g,z51:- Isolated from Multiple Abdominal Abscesses of an African Fat-Tailed Gecko, United States, 2020

subsp. ( ) is a common subspecies in reptiles and has been implicated as a source of serious and life-threatening diseases in humans. Although occurrence and significance of infections have been extensively studied, the genetic features of have remained unknown due to a lack of available high-quality genome sequences. We obtained the complete genome sequence of 45:g,z51:- strain 20-369 isolated from multiple abdominal abscesses of an African fat-tailed gecko ( ) using Nanopore and Illumina sequencing technologies and generated the 4.65Mbp complete genome sequence of the str. 20-369. We annotated and analyzed the genome sequence with the aim to gain a deeper understanding of the genome characteristics associated with its pathogenicity. Overall, this study found several interesting genomic features such as pseudogene formation, virulence gene profile, and novel genomic islands. This study provides basis for an understanding possible genetic mechanism underlying pathogenicity of 45:g,z51:- as well as a high-quality genome reference for future comparison studies.