Validation of the Use of Discharge Diagnostic Codes for the Verification of Secondary Atrial Fibrillation in Administrative Databases

“Secondary” atrial fibrillation (AF) denotes AF that is precipitated by short-term triggers and that may be reversible. Using administrative data to study secondary AF is of interest, but the ability of these data to verify secondary AF has not been studied. We conducted a cross-sectional analysis o...

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Veröffentlicht in:CJC open (Online) 2023-08, Vol.5 (8), p.597-602
Hauptverfasser: Nakajima, Erika, ShweikiAlrefaee, Bisan, Austin, Peter C., Ko, Dennis T., Abdel-Qadir, Husam
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Sprache:eng
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Zusammenfassung:“Secondary” atrial fibrillation (AF) denotes AF that is precipitated by short-term triggers and that may be reversible. Using administrative data to study secondary AF is of interest, but the ability of these data to verify secondary AF has not been studied. We conducted a cross-sectional analysis of 1000 randomly selected hospitalizations of patients discharged alive between January 1, 2016 and March 31, 2020, with AF coded as the most responsible diagnosis (type 1), post-admit comorbidity (type 2), or secondary diagnosis (type 3). We compared diagnosis types to AF category (secondary or not) as determined by a physician blinded to the discharge diagnosis type. We calculated the positive predictive value (PPV) of the designation of secondary AF in comparison to physician determination. A total of 421 hospitalizations had AF documented as a type 2 diagnosis; this had a PPV of 94.8% for physician determination of secondary AF. After excluding hospitalizations with preexisting AF, and those for which AF type could not be determined by the physician, the PPV of a type 2 diagnosis (n = 391) for secondary AF was 99.7%. Type 3 diagnoses of AF (n = 222) mostly captured hospitalizations with preexisting AF (87.8% of type 3 diagnoses). A type 2 diagnosis can be used to verify secondary AF in people who were first diagnosed with AF while hospitalized for other causes. This verification facilitates cohort studies and clinical trial recruitment of people with this AF subtype, although it should not be used to determine the prevalence or incidence of secondary AF. Une fibrillation auriculaire (FA) « secondaire » signifie que la FA est précipitée par des déclencheurs apparus depuis peu et pouvant être réversibles. L’utilisation de données administratives en vue d’étudier la FA secondaire peut être pertinente, mais la possibilité que ces données permettent d’évaluer les FA secondaires n’a pas été étudiée. Nous avons effectué une analyse transversale de 1 000 hospitalisations, sélectionnées au hasard, de patients ayant reçu leur congé alors qu’ils étaient en vie entre le 1er janvier 2016 et le 31 mars 2020, et dans le dossier desquels la FA était codée comme étant le diagnostic principal de l’hospitalisation (type 1), une affection concomitante diagnostiquée après l’admission à l’hôpital (type 2) ou un diagnostic secondaire (type 3). Nous avons comparé les types des diagnostics à la catégorie de FA (secondaire ou pas), déterminée par un médecin qui ignorait le type de dia
ISSN:2589-790X
2589-790X
DOI:10.1016/j.cjco.2023.05.007