Effect of fructooligosaccharide on humoral immunity induced by infectious bursal disease vaccine and some hematological parameters during aflatoxicosis in broiler chickens

The study was conducted to investigate the positive effects of prebiotic Fructo-oligosaccharide (FOS) on humoral immunity induced by infectious bursal disease (IBD) vaccine and some hematological parameters of broilers with and without feeding aflatoxin contaminated diet. A total number of 120 one day old unsexed Hubbard broiler chicks were used in this study till 42 days end of experiment, the chicks were randomly assigned according to diet supplementation into four groups (30 chicks for each) as follows: G1 Basal diet, G2 was fed basal diet plus prebiotic (FOS) 0.25g/kg, G3 have been treated with AFB1100 µg/kg, and G4 have been treated with AFB1100 µg/kg plus prebiotic (FOS) 0.25g/kg. Results of G2 showed a significant enhancement of the immune status, while hematological parameters such as red blood cell count (RBC), white blood cell count (WBC), hemoglobin concentration (Hb) and packed cell volume (PCV) were within normal values. G3 showed that AFB1 at 100 ppb broiler diet cause significant (P