Clinical outcome of assisted reproductive technologies in advanced aged men

The purpose was to establish whether the advanced male age may influence the outcomes in a controlled assisted reproductive technology (ART) program. This is an experimental study. Research and Clinical Center for Infertility of Yazd. A total of 63men undergoing ART cycles. In a retrospective study, the outcome of intracytoplasmic sperm injection (ICSI) in ART cycles in two groups of patients was studied. Patients regarding etiology of infertility were divided into two groups: (A) male factor infertility (n=47), and (B) female factor infertility (n=16). Sperm parameters, ART cycle characteristics and clinical outcomes were assessed between two groups. Clinical outcomes of ART in advanced aged men. There were no significant differences in rates of sperm count and morphology between two groups, but the rate of spermatozoa with progressive motility were higher in group B in comparison with A (P=0.002). The rates of high quality embryos, pregnancy and live birth showed no significant differences between the groups (P=0.4, P=0.4, P=0.2, respectively). It appears that the clinical outcome of ART in male and female factor infertility was not influenced by advanced paternal age.