Establishment of induced pluripotent stem cells from schizophrenia discordant fraternal twins

•Schizophrenia (SCZ) is one of the major psychiatric disorders.•We generated human iPSCs derived from a SCZ patient and from his twin brother.•These iPSCs will be useful to elucidate the pathomechanism of SCZ. Schizophrenia (SCZ) is one of the major psychiatric disorders. The genetic factor is certainly influential in the onset of the disease but is not decisive. There is no identified molecular/cellular marker of the disease, and the pathomechanism is still unknown. In this study, we generated human induced pluripotent stem cells (iPSCs) derived from SCZ-discordant fraternal twins, and they could contribute to elucidation of the pathomechanism of SCZ.