Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts

[...]out of the three O-Swiss that showed metastases, only one had been preceded by a primary tumour (MRD period of 36.5 weeks). [...]MRD-PDX developed by orthotopic implantation in NSG mice followed by surgical removal of the primary tumour accurately simulate the clinical behaviour of STS. ACKNOWLEDGEMENTS The authors would like to thank the nurses working at the operating theatre of the Ghent University Hospital and the residents of the pathology department for assisting in the collection of tumour material.