ERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in Wistar rats

ERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in Wistar rats

We investigated the influence of bone marrow cells upon activation of ERK ½ in an animal model of 90% PH. Phosphorylated ERK 1/2 was evaluated by western blot. No differences were found between the groups. Thus, increased survival does not appear to be mediated by ERK 1/2 activation. Keywords: MAP K...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clinical and Biomedical Research 2017-01, Vol.36 (4)
Hauptverfasser: Gustavo Alfredo Ochs de Muñoz, Nelson Alexandre Kretzmann, Mónica Luján López, Carlos Oscar Kieling, Carolina Uribe-Cruz, Luciano Basso da Silva, Alessandro Bersch Osvaldt, Ursula da Silveira Matte
Format: Artikel
Sprache:eng
Schlagworte:
acute liver failure
MAP Kinase Signaling System
stem cells
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We investigated the influence of bone marrow cells upon activation of ERK ½ in an animal model of 90% PH. Phosphorylated ERK 1/2 was evaluated by western blot. No differences were found between the groups. Thus, increased survival does not appear to be mediated by ERK 1/2 activation. Keywords: MAP Kinase Signaling System; stem cells; acute liver failure
ISSN:0101-5575
2357-9730