Evaluation of Tumor Budding in Predicting Survival for Gastric Carcinoma Patients in Vietnam

Background: Tumor budding (Bd) has been demonstrated to be a promising prognostic factor in many carcinomas and in gastric cancer. It may represent an optimal additional parameter that is helpful for risk stratification in gastric adenocarcinoma. Hence, the present research was designed to predict t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer control 2020-10, Vol.27 (1), p.1073274820968883
Hauptverfasser:	Dao, Tu Van, Nguyen, Chu Van, Nguyen, Quang Tien, Vu, Ha Thi Ngoc, Phung, Huyen Thi, Bui, Oanh Thi, Nguyen, Dung Khac, Luong, Bang Viet, Tran, Thuan Van
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - therapeutic use Capecitabine - therapeutic use Carcinoma Carcinoma - mortality Carcinoma - pathology Carcinoma - therapy Chemotherapy Chemotherapy, Adjuvant - methods Disease-Free Survival Female Follow-Up Studies Gastrectomy Gastric cancer Humans Kaplan-Meier Estimate Male Medical prognosis Middle Aged Neoplasm Recurrence, Local - epidemiology Neoplasm Recurrence, Local - pathology Original Research Paper Oxaloacetates - therapeutic use Patients Prognosis Retrospective Studies Risk Assessment - methods Stomach - pathology Stomach - surgery Stomach Neoplasms - mortality Stomach Neoplasms - pathology Stomach Neoplasms - therapy Surgery Survival Vietnam - epidemiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Background: Tumor budding (Bd) has been demonstrated to be a promising prognostic factor in many carcinomas and in gastric cancer. It may represent an optimal additional parameter that is helpful for risk stratification in gastric adenocarcinoma. Hence, the present research was designed to predict the survival outcomes of gastric cancer in Vietnam, applying the tumor budding criteria of the International Tumor Budding Consensus Conference (ITBCC) 2016. Methods: The present study was conducted on 109 gastric cancer patients who underwent surgery but did not receive neo-adjuvant chemotherapy from 2012 to 2015. The patients’ clinicopathological features were recorded. Bd was evaluated according to the 2016 ITBCC criteria and classified as Bd1 (0–4 buds), Bd2 (5–9 buds), and Bd3 (≥10 buds) grades, in addition to being categorized into 2 main Bd groups: low (
ISSN:	1073-2748 1526-2359 1526-2359 1073-2748
DOI:	10.1177/1073274820968883