TaiNi: Maximizing research output whilst improving animals’ welfare in neurophysiology experiments

Understanding brain function at the cell and circuit level requires representation of neuronal activity through multiple recording sites and at high sampling rates. Traditional tethered recording systems restrict movement and limit the environments suitable for testing, while existing wireless techn...

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Veröffentlicht in:	Scientific reports 2017-08, Vol.7 (1), p.8086-12, Article 8086
Hauptverfasser:	Jiang, Zhou, Huxter, John R., Bowyer, Stuart A., Blockeel, Anthony J., Butler, James, Imtiaz, Syed A., Wafford, Keith A., Phillips, Keith G., Tricklebank, Mark D., Marston, Hugh M., Rodriguez-Villegas, Esther
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/1453/2205 631/378/1595 9/30 Action Potentials - physiology Animal Welfare Animals Antennas Behavior, Animal - physiology Brain - physiology Brain research Electrophysiological Phenomena - physiology Electrophysiology - methods Experiments Female Humanities and Social Sciences Mice multidisciplinary Neurons - physiology Neurophysiology Neurophysiology - methods Recording Recording equipment Science Science (multidisciplinary) Wireless Technology
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Zusammenfassung:	Understanding brain function at the cell and circuit level requires representation of neuronal activity through multiple recording sites and at high sampling rates. Traditional tethered recording systems restrict movement and limit the environments suitable for testing, while existing wireless technology is still too heavy for extended recording in mice. Here we tested TaiNi, a novel ultra-lightweight (
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-017-08078-8