Management of disseminated bleeding in a patient with multiple malignomas using rotation thromboleastometry
[english] We report on a case of Klippel-Trenaunay syndrome with a histologically diagnosed dedifferentiated angiosarcoma. During operative tumor debulking, a disseminated bleeding developed which required a massive transfusion of red blood cell concentrates and therapeutic plasma. While plasmatic c...
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Veröffentlicht in: | GMS. German plastic, reconstructive and aesthetic surgery, burn and hand surgery reconstructive and aesthetic surgery, burn and hand surgery, 2014-04, Vol.4, p.Doc05 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | ger |
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Online-Zugang: | Volltext |
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Zusammenfassung: | [english] We report on a case of Klippel-Trenaunay syndrome with a histologically diagnosed dedifferentiated angiosarcoma. During operative tumor debulking, a disseminated bleeding developed which required a massive transfusion of red blood cell concentrates and therapeutic plasma. While plasmatic coagulation was within normal range, thromboelastometry showed a distinct hyperfibrinolysis. The bleeding was controlled by prolonged cauterisation and the substitution of tranexam acid as well as fresh frozen plasma. As a result of this treatment, hyperfibrinolysis showed complete restitution within a few hours. Histologically, a malignant peripheral nerve sheat tumor, a dedifferentiated angiosarcoma, a spindle cell sarcoma and an osteosarcoma were diagnosed within the tissue samples. |
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ISSN: | 2193-7052 2193-7052 |
DOI: | 10.3205/gpras000024 |