Contrast induced nephropathy after transcatheter aortic valve implantation

Background: Aortic stenosis ranks the third in the structure of all cardiovascular diseases, conceding only to arterial hypertension and coronary heart disease. Transcatheter aortic valve implantation (TAVI) is a promising area of interventional endovascular surgery that enables to provide surgical ...

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Veröffentlicht in:Alʹmanakh klinicheskoĭ medit͡s︡iny 2017-06, Vol.45 (3), p.242-246
Hauptverfasser: Kranin, D. L., Stets, V. V., Pestovskaya, O. R., Dunaev, E. P., Nazarov, D. A., Gaydukov, A. V., Mashtanov, G. V., Zamskiy, K. S., Fedorov, A. Yu, Varochkin, K. A., Kurnosov, S. A.
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Sprache:eng ; rus
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Zusammenfassung:Background: Aortic stenosis ranks the third in the structure of all cardiovascular diseases, conceding only to arterial hypertension and coronary heart disease. Transcatheter aortic valve implantation (TAVI) is a promising area of interventional endovascular surgery that enables to provide surgical care to a significant group of the patients with severe aortal stenosis.Aim: To assess the efficacy of prevention of the contrast induced nephropathy (CIN) in patients who underwent TAVI under general anesthesia.Materials and methods: We evaluated incidence of CIN in 19 patients who underwent surgery for aortic valve stenosis under general anesthesia with hemodilution and intravenous magnesium sulfate 1 g before administration of the contrast.Results: Laboratory signs of nephropathy within the first 72 hours after the intervention were found in 8/19 (42.1%) of patients. In 4 (50%) of patients with CIN, its risk had been very high, in 3 (38%), high, and in 1 (12%), moderate. The results obtained are compatible with the contrast-induced acute kidney injury risk estimated from the Mehran-Barrett-Parfrey scale.Conclusion: The used technique of hemodilution and magnesium-based prevention can be considered a safe method of CIN prophylaxis in TAVI patients.
ISSN:2072-0505
2587-9294
DOI:10.18786/2072-0505-2017-45-3-242-246