Effect of ATP and Bax on the apoptosis of Eimeria tenella host cells

Effect of ATP and Bax on the apoptosis of Eimeria tenella host cells

Eimeria tenella (E. tenella) is a species of Eimeria that causes haemorrhagic caecal coccidiosis, resulting in major economic losses in the global poultry industry. After E. tenella infection, the amount of ATP and Bax in host cells showed highly significant changes. Therefore, it is necessary to in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:BMC veterinary research 2017-12, Vol.13 (1), p.399-399, Article 399
Hauptverfasser: Xu, Zhiyong, Zheng, Mingxue, Zhang, Li, Zhang, Xuesong, Zhang, Yan, Cui, Xiaozhen, Gong, Xin, Xi, Rou, Bai, Rui
Format: Artikel
Sprache:eng
Schlagworte:
adenosine triphosphate
Apoptosis
ATP
Bax
cecum
coccidiosis
Eimeria tenella
financial economics
flow cytometry
Health aspects
Host cell
Infection
mitochondria
necrosis
Permeability
Poultry industry
staining
veterinary medicine
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Eimeria tenella (E. tenella) is a species of Eimeria that causes haemorrhagic caecal coccidiosis, resulting in major economic losses in the global poultry industry. After E. tenella infection, the amount of ATP and Bax in host cells showed highly significant changes. Therefore, it is necessary to investigate the effects of ATP and Bax on the apoptosis of E. tenella host cells. The ATP-treated group and the V5-treated group had higher E. tenella infection rates than the untreated group at 24, 48, 72, 96, and 120 h after infection with E. tenella. The results of flow cytometry showed that compared with the control group, the mitochondrial permeability transition pore (MPTP) opening in the untreated group was highly significantly increased (P 
ISSN:1746-6148
1746-6148
DOI:10.1186/s12917-017-1313-z