Immune reconstitution inflammatory syndrome‐associated lymphoma: A retrospective Brazilian cohort

After initiating combined antiretroviral therapy (cART), individuals with human immunodeficiency virus (HIV) may develop Hodgkin/non‐Hodgkin lymphoma due to immune reconstitution inflammatory syndrome (IRIS). This retrospective cohort study evaluated the incidence, clinical features and prognosis of...

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Veröffentlicht in:	EJHaem 2024-02, Vol.5 (1), p.147-152
Hauptverfasser:	Vargas, Juliano Cordova, Cecyn, Karin Zattar, Oliveira Marques, Mariana, Pereira, Juliana, Tobias Braga, Walter M., Hamerschlak, Nelson, Tabacof, Jacques, Liz, Caina D., Abdo, André, Ferreira, Paulo Roberto Abrão, Colleoni, Gisele W. Braga, Baiocchi, Otavio C. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiretroviral therapy Antiviral agents Bacterial infections Biopsy Bone marrow Cancer therapies Chemotherapy Development and progression Diagnosis Drug therapy Hepatitis Highly active antiretroviral therapy HIV HIV (Viruses) HIV patients Human immunodeficiency virus Immune reconstitution immune reconstitution inflammatory syndrome Immune system Infections Inflammation Lymphocytes Lymphoma Males Medical prognosis Nervous system Non-Hodgkin's lymphoma Non-Hodgkin's lymphomas Oncology Prognosis Vincristine
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Zusammenfassung:	After initiating combined antiretroviral therapy (cART), individuals with human immunodeficiency virus (HIV) may develop Hodgkin/non‐Hodgkin lymphoma due to immune reconstitution inflammatory syndrome (IRIS). This retrospective cohort study evaluated the incidence, clinical features and prognosis of IRIS‐associated lymphomas in Brazilian patients. Incidence in 2000–2019 was 9.8% (27/276 patients with HIV and lymphoma; viral load drop >1 log). Time between HIV diagnosis and cART initiation was
ISSN:	2688-6146 2688-6146
DOI:	10.1002/jha2.835