Design and Synthesis of an Indole-Estrogen Derivative

Design and Synthesis of an Indole-Estrogen Derivative

There are several methods reported for synthesis of aromatic-condensed derivatives; nevertheless, expensive reagents and special conditions are required. Therefore, in this study, an indole-estrogen derivative (3-[4-(2-butyl-3-cyclohexylimino-4-piperidin-1-yl-cyclobutylidencarbamoyl)]-phenoxy-NH-ind...

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Veröffentlicht in:Journal of chemistry 2014-01, Vol.2014 (2014), p.1-7
Hauptverfasser: Betty, Sarabia-Alcocer, Elodia, García-Cervera, Lenin, Hau-Heredia, Marcela, Rosas-Nexticapa, Francisco, Díaz-Cedillo, Lauro, Figueroa-Valverde, Eduardo, Pool-Gómez
Format: Artikel
Sprache:eng
Schlagworte:
Chemical properties
Chemical synthesis
Estrogen
Methods
Production processes
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Zusammenfassung:There are several methods reported for synthesis of aromatic-condensed derivatives; nevertheless, expensive reagents and special conditions are required. Therefore, in this study, an indole-estrogen derivative (3-[4-(2-butyl-3-cyclohexylimino-4-piperidin-1-yl-cyclobutylidencarbamoyl)]-phenoxy-NH-indolo[2′,3′:17,16]estra-1,3,5(10)triene) was synthesized using some strategies. The structure of all compounds obtained was confirmed by spectroscopic and spectrometric methods. In conclusion, a facile procedure for the formation of an indole-estrogen derivative was developed in this study.
ISSN:2090-9063
2090-9071
DOI:10.1155/2014/460968