Prolonged treatment of neuroendocrine carcinoma of the cervix with a PARP inhibitor based on next generation sequencing

Prolonged treatment of neuroendocrine carcinoma of the cervix with a PARP inhibitor based on next generation sequencing

•Next generation sequencing identified a BRCA 2 mutation in a patient with stage IVB neuroendocrine cancer of the cervix.•Treatment with rucaparib resulted in disease stabilization for 74 months.•The patient remains fully active working full time as a nurse and pursing a nurse practitioner degree....

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Veröffentlicht in:Gynecologic oncology reports 2024-08, Vol.54, p.101458, Article 101458
1. Verfasser: Rose, Peter G.
Format: Artikel
Sprache:eng
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Zusammenfassung:•Next generation sequencing identified a BRCA 2 mutation in a patient with stage IVB neuroendocrine cancer of the cervix.•Treatment with rucaparib resulted in disease stabilization for 74 months.•The patient remains fully active working full time as a nurse and pursing a nurse practitioner degree.
ISSN:2352-5789
2352-5789
DOI:10.1016/j.gore.2024.101458