Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome

Trinucleotide repeat expansion diseases such as fragile X syndrome are of great interest to study since the mechanism of its development is still unknown. IPS cell lines are some of the most convenient models for studying. The ICGi032-A iPS cell line was obtained from the peripheral blood mononuclea...

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Veröffentlicht in:	Stem cell research 2021-12, Vol.57, p.102615-102615, Article 102615
Hauptverfasser:	Gridina, M.M., Shitik, E.M., Lemskaya, N.A., Minina, J.M., Grishchenko, I.V., Dolskiy, A.A., Shorina, A.R., Maksimova, Y.V., Yudkin, D.V.
Format:	Artikel
Sprache:	eng
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Zusammenfassung:	Trinucleotide repeat expansion diseases such as fragile X syndrome are of great interest to study since the mechanism of its development is still unknown. IPS cell lines are some of the most convenient models for studying. The ICGi032-A iPS cell line was obtained from the peripheral blood mononuclear cells of the patient affected with fragile X syndrome. ICGi032-A iPS cell line have a normal karyotype, expression of pluripotency markers and can differentiate in vitro into the cells of three germ layers.
ISSN:	1873-5061 1876-7753
DOI:	10.1016/j.scr.2021.102615