Point Prevalence Survey of Antimicrobial Utilization in Ghana's Premier Hospital: Implications for Antimicrobial Stewardship

The first comprehensive point prevalence survey at the Korle Bu Teaching Hospital (KBTH) was performed as part of the 2019 Global Point Prevalence Survey (Global-PPS) on antimicrobials. The aim was to establish a PPS baseline for the whole hospital and to identify required stewardship interventions....

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Veröffentlicht in:Antibiotics (Basel) 2021-12, Vol.10 (12), p.1528
Hauptverfasser: Ankrah, Daniel, Owusu, Helena, Aggor, Asiwome, Osei, Anthony, Ampomah, Agneta, Harrison, Mark, Nelson, Frempomaa, Aboagye, Grace Owusu, Ekpale, Priscilla, Laryea, Jennifer, Selby, Julia, Amoah, Serwaa, Lartey, Linda, Addison, Okaikor, Bruce, Elizabeth, Mahungu, Joyce, Mirfenderesky, Mariyam
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Sprache:eng
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Zusammenfassung:The first comprehensive point prevalence survey at the Korle Bu Teaching Hospital (KBTH) was performed as part of the 2019 Global Point Prevalence Survey (Global-PPS) on antimicrobials. The aim was to establish a PPS baseline for the whole hospital and to identify required stewardship interventions. The PPS was conducted over three days in June 2019 using the GLOBAL-PPS standardized method for surveillance of antimicrobial utilization in hospitals to evaluate antimicrobial prescribing. In all, 988 patients were admitted to 69 wards. Overall antimicrobial prevalence was 53.3%. More community-acquired infections (CAI) were treated empirically compared to health-care associated infections (94.0% vs. 86.1% respectively, = 0.002). Main indications for prescribing antimicrobials were pneumonia (18.4%), skin and soft tissue infections (11.4%) and sepsis (11.1%). Among antimicrobials, systemic antibiotics accounted for 83.5%, of which amoxicillin with beta-lactam inhibitor (17.5%), metronidazole (11.8%) and ceftriaxone (11.5%) dominated. Guideline compliance was 89.0%. Stop/review dates were completed in 33.4% and documented reason was recorded in 53.0% of all prescriptions. If the findings in this PPS can be addressed antimicrobial stewardship at the KBTH stands to improve significantly.
ISSN:2079-6382
2079-6382
DOI:10.3390/antibiotics10121528