Effect of hemoglobin content on cerebral oxygen saturation during surgery for scoliosis in pediatric patients

Although regional cerebral oxygen saturation (rScO ) monitoring has been widely used in clinical practice, the relationship between hemoglobin (dHB) content and rScO is incompletely understood. The aim of this study was to analyze the effect of hemoglobin content on rScO in pediatric patients undergoing general anesthesia for correction of scoliosis. Ninety-two pediatric patients aged 3 to 14 years undergoing scoliosis correction surgery were enrolled. Continuous monitoring of bilateral regional cerebral oxygen saturation by near-infrared spectroscopy (NIRS, CASMED, USA) was performed after entering the operation room. rScO was recorded when the patients entered the operating room (T , baseline), after anesthesia induced intubation (T ), and after radial artery puncture (T ). The lowest value of rScO during surgery was also recorded. The arterial blood pressure (ABP), heart rate (HR), pulse oxygen saturation (SpO ), end tidal carbon dioxide partial pressure (PetCO ) were continuously recorded. Patients were classified as low rScO or high rScO group according to whether the lowest intraoperative rScO was 15% lower than the baseline value. An analysis and comparison of differences in hemoglobin content in these two groups was carried out. The preoperative hemoglobin-postoperative hemoglobin of patients in the high rScO group was significantly lower than that in the low rScO group (t = - 7.86, p