VIPoma: a rare cause of diarrhea. A case report

Introduction: Vasoactive intestinal peptide-secreting tumor (VIPoma) is a rare functional pancreatic neuroendocrine tumor (F-PNET) characterized by secretory diarrhea, hypokalemia, and hypochlorhydria. Its low incidence and high risk of malignancy pose a clinical challenge that requires a high degre...

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Veröffentlicht in:	Revista de la Facultad de Medicina, Universidad Nacional de Colombia Universidad Nacional de Colombia, 2021-07, Vol.69 (3)
Hauptverfasser:	Sánchez-Salazar, Sara María, Torres-Alzate, Santiago, Muñoz-Cortés, Viviana Marcela, Builes-Barrera, Carlos Alfonso, Gutiérrez-Montoya, Jorge Iván, Román-González, Alejandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis Case Report Case reports Diarrhea Hypokalemia MEDICINE, GENERAL & INTERNAL Pancreatic cancer Peptides Vasoactive Intestinal Peptide Vipoma
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Zusammenfassung:	Introduction: Vasoactive intestinal peptide-secreting tumor (VIPoma) is a rare functional pancreatic neuroendocrine tumor (F-PNET) characterized by secretory diarrhea, hypokalemia, and hypochlorhydria. Its low incidence and high risk of malignancy pose a clinical challenge that requires a high degree of clinical suspicion. Case presentation: A 61-year-old woman visited the emergency department of a tertiary care hospital in Medellín, Colombia, due to chronic diarrhea (7 months) that led to dehydration, renal failure, metabolic acidosis, and hypokalemia. As a result, a treatment based on loperamide, intravenous fluids and broad-spectrum antibiotics was started. In addition, chromogranin A levels of 477 ug/L (
ISSN:	0120-0011 2357-3848
DOI:	10.15446/revfacmed.v69n3.81603