Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium

Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium

Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [18F]GE180 binding of rodent brain and myocardium by blocking experiments w...

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Veröffentlicht in:Data in brief 2018-08, Vol.19, p.331-336
Hauptverfasser: Deussing, Maximilian, Blume, Tanja, Vomacka, Lena, Mahler, Christoph, Focke, Carola, Todica, Andrei, Unterrainer, Marcus, Albert, Nathalie L., Lindner, Simon, von Ungern-Sternberg, Barbara, Baumann, Karlheinz, Zwergal, Andreas, Bartenstein, Peter, Herms, Jochen, Rominger, Axel, Brendel, Matthias
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Sprache:eng
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Neuroscience
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Zusammenfassung:Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [18F]GE180 binding of rodent brain and myocardium by blocking experiments with prior application of non-radioactive GE180, using dynamic in vivo positron-emission-tomography and ex vivo gamma counter measurements. Expression of TSPO was compared between rodent brain and myocardium by quantitative polymerase chain reaction.
ISSN:2352-3409
2352-3409
DOI:10.1016/j.dib.2018.04.133