Management of a solitary tongue nodule

[2] The malignant type is diagnosed by the presence of histological criteria like necrosis, distribution of the cells in fusiform strings, large nucleus with vesicular core, increased mitotic activity, increased nucleus radius in relations to cytoplasm and nuclear pleomorphism; [3] rarely, it can present metastasis. Since Abrikossoff's tumor is one of the most common granular cell lesion of the head and neck, it is important to differentiate it from other tumors of the oral cavity containing granular cells like odontogenic granular cell fibroma, granular cell ameloblastoma, fibroxanthoma, angiosarcoma, and carcinoma of the basaloid cells.