Presence of secondary bladder cancer following radical nephroureterectomy for upper tract urothelial carcinoma: characteristics, risk factors, and predictive value

To assess the characteristics, predictive risk factors, and prognostic effect of secondary bladder cancer (SBCa) following radical nephroureterectomy (RNU) in upper tract urothelial carcinoma (UTUC). Using the Surveillance, Epidemiology, and End Results database, the authors analyzed clinicopatholog...

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Veröffentlicht in:	BMC urology 2022-12, Vol.22 (1), p.211-211, Article 211
Hauptverfasser:	Lai, Shicong, Wu, Pengjie, Liu, Shengjie, Seery, Samuel, Liu, Jianyong, He, Lei, Liu, Ming, Zhang, Yaoguang, Wang, Jian-Ye, Xu, Tao
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cancer Cancer-specific survival Carcinoma Carcinoma, Transitional Cell - pathology Epidemiology Humans Medical research Medicine, Experimental Neoplasm Recurrence, Local - surgery Nephroureterectomy - methods Prognosis Radical nephroureterectomy Retrospective Studies Risk Factors Secondary bladder cancer characteristics Upper urinary tract urothelial carcinoma Ureteral Neoplasms - pathology Urinary Bladder Neoplasms - surgery
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Zusammenfassung:	To assess the characteristics, predictive risk factors, and prognostic effect of secondary bladder cancer (SBCa) following radical nephroureterectomy (RNU) in upper tract urothelial carcinoma (UTUC). Using the Surveillance, Epidemiology, and End Results database, the authors analyzed clinicopathologic characteristics and survival data from 472 UTUC patients with SBCa after RNU, between 2004 and 2017. Cox's proportional hazard regression model was implemented to identify independent predictors associated with post-recurrence outcomes. The threshold for statistical significance was p
ISSN:	1471-2490 1471-2490
DOI:	10.1186/s12894-022-01158-6