Co-infection with Zika and Chikungunya viruses associated with fetal death—A case report

•Zika and Chikungunya viruses are transmitted by the same vector (Aedes aegypti), and co-infection by these viruses is possible.•These arboviral infections during pregnancy can lead to fetal death.•Zika virus was found in fetal kidney. We describe a case of fetal death associated with a recent infec...

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Veröffentlicht in:International journal of infectious diseases 2018-07, Vol.72, p.25-27
Hauptverfasser: Prata-Barbosa, Arnaldo, Cleto-Yamane, Thaís Lira, Robaina, Jaqueline Rodrigues, Guastavino, Andrea Bittencourt, de Magalhães-Barbosa, Maria Clara, Brindeiro, Rodrigo de Moraes, Medronho, Roberto Andrade, da Cunha, Antonio José Ledo Alves
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Sprache:eng
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Zusammenfassung:•Zika and Chikungunya viruses are transmitted by the same vector (Aedes aegypti), and co-infection by these viruses is possible.•These arboviral infections during pregnancy can lead to fetal death.•Zika virus was found in fetal kidney. We describe a case of fetal death associated with a recent infection by Chikungunya virus (CHIKV) in a Brazilian pregnant woman (positive RT-PCR in blood and placenta). Zika virus (ZIKV) infection during pregnancy was also identified, based on a positive RT-PCR in a fetal kidney specimen. The maternal infection caused by the ZIKV was asymptomatic and the CHIKV infection had a classical clinical presentation. The fetus had no apparent anomalies, but her weight was between the 3rd and 10th percentile for the gestational age. This is the second case report of congenital arboviral co-infection and the first followed by antepartum fetal death.
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2018.04.4320