Short DNA Oligonucleotide as a Ag+ Binding Detector

Short DNA Oligonucleotide as a Ag+ Binding Detector

Ag+ has been known to mediate several natural metallo-base pairs. Based on the unique structural information of a short 8-mer DNA strand (5′-GCACGCGC-3′) induced by Ag+, we constructed several fluorescent DNA beacons for the detection of Ag+ according to the increase in the fluorescence emission on...

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Veröffentlicht in:ACS omega 2020-11, Vol.5 (44), p.28565-28570
Hauptverfasser: Shen, Fusheng, Mao, Song, Mathivanan, Johnsi, Wu, Ying, Chandrasekaran, Arun Richard, Liu, Hehua, Gan, Jianhua, Sheng, Jia
Format: Artikel
Sprache:eng
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Zusammenfassung:Ag+ has been known to mediate several natural metallo-base pairs. Based on the unique structural information of a short 8-mer DNA strand (5′-GCACGCGC-3′) induced by Ag+, we constructed several fluorescent DNA beacons for the detection of Ag+ according to the increase in the fluorescence emission on Ag+ binding. This Ag+ detection assay is quick, sensitive, and easy to adapt and can function in a wide range of temperatures from 5 to 65 °C.
ISSN:2470-1343
2470-1343
DOI:10.1021/acsomega.0c03372