Myocarditis following mRNA vaccination against SARS-CoV-2, a case series

mRNA COVID-19 vaccines have emerged as a new form of vaccination that has proven to be highly safe and effective against COVID-19 vaccination. Rare adverse events including myocarditis have been reported in the literature. Data were gathered from the electronic medical record of four patients personally treated by the authors. Four patients, ages 20 to 30, presented with myocarditis characterized by chest pain, elevations in troponin-I and C-reactive protein, and negative viral serologies two to four days following mRNA vaccine administration. One had a cardiac MRI showing delayed gadolinium enhancement in a subpericardial pattern. All experienced symptom resolution by the following day, and the two who have returned for follow-up had normal troponin-I and CRP values. Along with previously reported instances, these cases raise suspicion for a possible link between mRNA vaccines and myocarditis.