Research progress on the role of IgG N-glycosylation modification in diabetic retinopathy

Research progress on the role of IgG N-glycosylation modification in diabetic retinopathy

Diabetic retinopathy (DR) is an immune-inflammatory disease and immunoglobulin G(IgG) N-glycosylation modifications are closely associated with DR. Among them, the modification of galactosylation, fucosylation, sialylation and bisecting N-acetylglucosamine of IgG changed has been proved to be predis...

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Veröffentlicht in:Ji chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics 2023-03, Vol.43 (3), p.509-513
1. Verfasser: ZHANG Yixin, CAI Shanjun, LI Zhili, YU Weihong, ZHANG Hua
Format: Artikel
Sprache:chi
Schlagworte:
diabetic retinopathy|immunoglobulin g|glycosylation modification
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Zusammenfassung:Diabetic retinopathy (DR) is an immune-inflammatory disease and immunoglobulin G(IgG) N-glycosylation modifications are closely associated with DR. Among them, the modification of galactosylation, fucosylation, sialylation and bisecting N-acetylglucosamine of IgG changed has been proved to be predisposing factor to stimulate inflammation and related retinopathy.
ISSN:1001-6325
DOI:10.16352/j.issn.1001-6325.2023.03.509