Influence of maternal periuterine and periovarian fat on reproductive performance and fetal growth in rats

We aimed to evaluate how high-fat diet consumption can interfere with rat reproductive performance and fetal development. High-fat diet (HFD) was initiated in 30-day-old rats, distributed into two groups (n=7 animals/group): Rats receiving a standard diet and rats receiving HFD. At adulthood, the ra...

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Veröffentlicht in:Anais da Academia Brasileira de Ciências 2023-01, Vol.95 (suppl 2), p.e20230079-e20230079
Hauptverfasser: Gomes, Maria Eduarda P, Didomizio, Luigi M J, Sinzato, Yuri K, Paula, Verônyca G, Souza, Maysa R, Gallego, Franciane Q, Barco, Vinícius S, Volpato, Gustavo T, Damasceno, Débora Cristina
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Sprache:eng
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Zusammenfassung:We aimed to evaluate how high-fat diet consumption can interfere with rat reproductive performance and fetal development. High-fat diet (HFD) was initiated in 30-day-old rats, distributed into two groups (n=7 animals/group): Rats receiving a standard diet and rats receiving HFD. At adulthood, the rats were mated, and on day 21 of pregnancy, the females were anesthetized, decapitated, and submitted to laparotomy to obtain visceral and periovarian adipose tissue. The uterine horns were exposed for analysis of maternal reproductive performance. The fetuses and placentas were weighed and analyzed. Pearson's correlation test was used, and p
ISSN:0001-3765
1678-2690
1678-2690
DOI:10.1590/0001-3765202320230079