Lung neoplasm diagnostics using Raman spectroscopy and autofluorescence analysis

Lung neoplasm diagnostics using Raman spectroscopy and autofluorescence analysis

A method of lung neoplasm diagnostics is proposed based on the combined analysis of Raman and autofluorescence spectra excited by laser beam with the wavelength 785 nm. Such approach allows fast selection of the pathology region followed by differentiation of the neoplasm type. The developed method...

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Veröffentlicht in:Journal of biomedical photonics & engineering 2015-03, Vol.1 (1), p.70-76
Hauptverfasser: Artemyev, Dmitry N, Zakharov, Valery P, Bratchenko, Ivan A, Myakinin, Oleg O, Kornilin, Dmitry V, Kozlov, Sergey V, Moryatov, Alexander A
Format: Artikel
Sprache:eng
Schlagworte:
autofluorescence
lung cancer
optical diagnostics for medicine
Raman spectroscopy
spectroscopy
tissue diagnostics
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Zusammenfassung:A method of lung neoplasm diagnostics is proposed based on the combined analysis of Raman and autofluorescence spectra excited by laser beam with the wavelength 785 nm. Such approach allows fast selection of the pathology region followed by differentiation of the neoplasm type. The developed method demonstrated the sensitivity of 90.9% and the specificity of 71.4% in the differentiation of squamous cell carcinoma and adenocarcinoma cases.
ISSN:2411-2844
2411-2844
DOI:10.18287/JBPE-2015-1-1-70