Castleman's Disease : A Case Report of the Unicentric Type

Castleman's disease, or angiofollicular lymph node hyperplasia, is a relatively rare disorder characterized by the benign proliferation of lymphoid tissue related to the chronic human herpes virus 8 (HHV-8) infection and the human immunodeficiency virus (HIV). Two clinical entities have been de...

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Veröffentlicht in:Case reports in surgery 2012-01, Vol.2012 (2012), p.1-3
Hauptverfasser: Larrañaga, E., Gomez-Ramirez, J., Martin, J. L., Garcia, I., Del Campo, L., Posada, M., Sanchez-Urdazpal, L., Martin-Perez, E.
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Sprache:eng
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Zusammenfassung:Castleman's disease, or angiofollicular lymph node hyperplasia, is a relatively rare disorder characterized by the benign proliferation of lymphoid tissue related to the chronic human herpes virus 8 (HHV-8) infection and the human immunodeficiency virus (HIV). Two clinical entities have been described: a unicentric presentation with the disease confined to a single anatomic lymph node and a multicentric presentation characterized by generalized lymphadenopathy and a more aggressive clinical course. Also, three histopathological subtypes have been described: hyaline-vascular, plasma cell, and a mixed variant. Preoperative diagnosis of hyaline-vascular Castleman's disease is difficult, and the definitive result is based on postoperative pathological findings. The gold standard therapy is the complete surgical excision.
ISSN:2090-6900
2090-6919
DOI:10.1155/2012/175272