Association between low body mass index and increased 28-day mortality of severe sepsis in Japanese cohorts

Current research regarding the association between body mass index (BMI) and altered clinical outcomes of sepsis in Asian populations is insufficient. We investigated the association between BMI and clinical outcomes using two Japanese cohorts of severe sepsis (derivation cohort, Chiba University Ho...

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Veröffentlicht in:Scientific reports 2021-01, Vol.11 (1), p.1615-7, Article 1615
Hauptverfasser: Oami, Takehiko, Karasawa, Satoshi, Shimada, Tadanaga, Nakada, Taka-aki, Abe, Toshikazu, Ogura, Hiroshi, Shiraishi, Atsushi, Kushimoto, Shigeki, Saitoh, Daizoh, Fujishima, Seitaro, Mayumi, Toshihiko, Shiino, Yasukazu, Tarui, Takehiko, Hifumi, Toru, Otomo, Yasuhiro, Okamoto, Kohji, Umemura, Yutaka, Kotani, Joji, Sakamoto, Yuichiro, Sasaki, Junichi, Shiraishi, Shin-ichiro, Takuma, Kiyotsugu, Tsuruta, Ryosuke, Hagiwara, Akiyoshi, Yamakawa, Kazuma, Masuno, Tomohiko, Takeyama, Naoshi, Yamashita, Norio, Ikeda, Hiroto, Ueyama, Masashi, Fujimi, Satoshi, Gando, Satoshi
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Sprache:eng
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Zusammenfassung:Current research regarding the association between body mass index (BMI) and altered clinical outcomes of sepsis in Asian populations is insufficient. We investigated the association between BMI and clinical outcomes using two Japanese cohorts of severe sepsis (derivation cohort, Chiba University Hospital, n = 614; validation cohort, multicenter cohort, n = 1561). Participants were categorized into the underweight (BMI 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-80284-3