Injury to white matter tracts in relapsing-remitting multiple sclerosis: A possible therapeutic window within the first 5 years from onset using diffusion-tensor imaging tract-based spatial statistics

DTI studies in multiple sclerosis (MS) reveal white matter (WM) injury that occurs with disease progression. In the present study we aimed to elucidate the relationship of microstructural WM damage in patients with varying periods of disease duration. DTI scans were acquired from 90 MS patients and...

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Veröffentlicht in:NeuroImage clinical 2015-01, Vol.8 (C), p.261-266
Hauptverfasser: Asaf, Achiron, Evan, Stone, Anat, Achiron
Format: Artikel
Sprache:eng
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Zusammenfassung:DTI studies in multiple sclerosis (MS) reveal white matter (WM) injury that occurs with disease progression. In the present study we aimed to elucidate the relationship of microstructural WM damage in patients with varying periods of disease duration. DTI scans were acquired from 90 MS patients and 25 healthy controls. Patients were grouped to short (
ISSN:2213-1582
2213-1582
DOI:10.1016/j.nicl.2015.04.020