Draft genome sequence of a uropathogenic Escherichia coli isolate (ST38 O1:H15) from Pakistan, an emerging multidrug-resistant sequence type with a high virulence profile

Draft genome sequence of a uropathogenic Escherichia coli isolate (ST38 O1:H15) from Pakistan, an emerging multidrug-resistant sequence type with a high virulence profile

Abstract Sequence type 38 is considered a uropathogenic Escherichia coli /enteroaggregative E. coli hybrid associated with multidrug resistance and urinary tract infections. The draft genome sequence of UEC59 from a woman in Pakistan revealed a 5 324 938 bp genome with 5386 coding sequences (CDS), 8...

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Veröffentlicht in:New microbes and new infections 2019-01, Vol.27, p.1-2
Hauptverfasser: Rafaque, Z, Dasti, J.I, Andrews, S.C
Format: Artikel
Sprache:eng
Schlagworte:
Draft genome
Infectious Disease
MDR
Pakistan
ST38
Taxonogenomics: Genome of a Known Organism
UPEC
virulence
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Zusammenfassung:Abstract Sequence type 38 is considered a uropathogenic Escherichia coli /enteroaggregative E. coli hybrid associated with multidrug resistance and urinary tract infections. The draft genome sequence of UEC59 from a woman in Pakistan revealed a 5 324 938 bp genome with 5386 coding sequences (CDS), 86 transfer RNA genes and multiple antibiotic resistance genes ( blaTEM-1 , CMY-2, sul1, sul2, dfrA17, tetA, mphA ) and mobile elements ( int1, two transposons, 30 insertion sequence elements, one integrative conjugative element, four plasmids, five prophages), along with many virulence genes.
ISSN:2052-2975
2052-2975
DOI:10.1016/j.nmni.2018.10.004