Serial magnetic resonance imaging and ultrasound examinations demonstrate differential inflammatory lesion patterns in soft tissue and bone upon patient-reported flares in rheumatoid arthritis

Magnetic resonance imaging (MRI) and ultrasonography (US) are more sensitive than clinical evaluation in assessing inflammation in rheumatoid arthritis (RA). Data is scarce regarding potential link between patient-reported flares and inflammation on imaging. The aim of the study was to explore the p...

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Veröffentlicht in:	Arthritis research & therapy 2020-02, Vol.22 (1), p.19-19, Article 19
Hauptverfasser:	Kuettel, Dorota, Glinatsi, Daniel, Østergaard, Mikkel, Terslev, Lene, Primdahl, Jette, Möller, Sören, Pedersen, Andreas, Petersen, Randi, Weber, Ulrich, Hørslev-Petersen, Kim
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis Diagnosis Diagnostic imaging Disease Edema Inflammation Laboratories Magnetic resonance imaging Medical examination MRI Outpatient care facilities Patient-reported flares Patients Questionnaires Rheumatoid arthritis Rheumatoid factor Rheumatology Synovitis Tendons Tenosynovitis Ultrasonography Ultrasound imaging Wrist
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Zusammenfassung:	Magnetic resonance imaging (MRI) and ultrasonography (US) are more sensitive than clinical evaluation in assessing inflammation in rheumatoid arthritis (RA). Data is scarce regarding potential link between patient-reported flares and inflammation on imaging. The aim of the study was to explore the pattern and longitudinal associations of inflammatory lesions detected by serial MRI and US in relation to patient-reported flares in patients with RA. Eighty RA patients with baseline DAS28CRP 14 days. Independent associations were observed between patient-reported flares and tenosynovitis by MRI and US (p
ISSN:	1478-6362 1478-6354 1478-6362
DOI:	10.1186/s13075-020-2105-6