The resolution of anemia after curative parathyroidectomy is sustained even after a decade

{Table 1} It is known that elevated parathyroid hormone (PTH) levels correlate with anemia in patients with chronic kidney disease and this persistently elevated PTH leads to marrow fibrosis. [3] The mechanism of anemia in PHPT is multifactorial, including a direct inhibitory effect of PTH on erythr...

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Veröffentlicht in:Indian journal of endocrinology and metabolism 2015-09, Vol.19 (5), p.691-692
Hauptverfasser: Bhadada, Sanjay Kumar, Arya, Ashutosh Kumar, Parthan, Girish, Singh, Priyanka
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Sprache:eng
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Zusammenfassung:{Table 1} It is known that elevated parathyroid hormone (PTH) levels correlate with anemia in patients with chronic kidney disease and this persistently elevated PTH leads to marrow fibrosis. [3] The mechanism of anemia in PHPT is multifactorial, including a direct inhibitory effect of PTH on erythropoietin synthesis and bone marrow erythroid progenitors, and PTH-induced bone marrow fibrosis, which is mediated by the effect of increased cytokines (interleukin-6 and tumor necrosis factor-α).
ISSN:2230-8210
2230-9500
DOI:10.4103/2230-8210.163215