The resolution of anemia after curative parathyroidectomy is sustained even after a decade
{Table 1} It is known that elevated parathyroid hormone (PTH) levels correlate with anemia in patients with chronic kidney disease and this persistently elevated PTH leads to marrow fibrosis. [3] The mechanism of anemia in PHPT is multifactorial, including a direct inhibitory effect of PTH on erythr...
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Veröffentlicht in: | Indian journal of endocrinology and metabolism 2015-09, Vol.19 (5), p.691-692 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | {Table 1} It is known that elevated parathyroid hormone (PTH) levels correlate with anemia in patients with chronic kidney disease and this persistently elevated PTH leads to marrow fibrosis. [3] The mechanism of anemia in PHPT is multifactorial, including a direct inhibitory effect of PTH on erythropoietin synthesis and bone marrow erythroid progenitors, and PTH-induced bone marrow fibrosis, which is mediated by the effect of increased cytokines (interleukin-6 and tumor necrosis factor-α). |
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ISSN: | 2230-8210 2230-9500 |
DOI: | 10.4103/2230-8210.163215 |