A perplexing primary novel hilar lesion: Remember the pneumonic PPNHL

A 60-year-old female presented with dyspnea, cough, and chest pain with a left hilar mass lesion. In our case, clinicoradiological correlation, bronchoscopy, and computed tomography-guided biopsy revealed the diagnosis of primary pulmonary non-Hodgkin's lymphoma (PPNHL) on histopathology and im...

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Veröffentlicht in:	Indian journal of pathology & microbiology 2018-01, Vol.61 (1), p.85-89
Hauptverfasser:	Utpat, Ketaki, Desai, Unnati, Amonkar, Gayathri, Joshi, Jyotsna
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Alkylating - therapeutic use Antineoplastic Combined Chemotherapy Protocols Biopsy Bronchoscopy Bronchoscopy - methods Calcification Care and treatment Case studies Chemotherapy Computed tomography Cough Cyclophosphamide Cyclophosphamide - therapeutic use Cysts Diagnosis Doxorubicin Doxorubicin - therapeutic use Dyspnea Female flexible fiberoptic bronchoscopy Gene expression Histopathology Humans Immunohistochemistry Lung Neoplasms - diagnosis Lung Neoplasms - diagnostic imaging Lung Neoplasms - drug therapy Lung Neoplasms - physiopathology Lungs Lymphatic system Lymphoma Lymphoma, B-Cell, Marginal Zone - diagnosis Lymphoma, B-Cell, Marginal Zone - drug therapy Lymphoma, B-Cell, Marginal Zone - pathology Lymphoma, Non-Hodgkin - diagnosis Lymphoma, Non-Hodgkin - diagnostic imaging Lymphoma, Non-Hodgkin - drug therapy Male Middle Aged Mucosa Mucosal-associated lymphoid tissue Non-Hodgkin's lymphoma Non-Hodgkin's lymphomas Pain Pneumonia Prednisolone primary pulmonary non-Hodgkin's lymphoma Pulmonary arteries Respiration Thyroid gland Tomography, Emission-Computed Tumors Vincristine
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Beschreibung
Zusammenfassung:	A 60-year-old female presented with dyspnea, cough, and chest pain with a left hilar mass lesion. In our case, clinicoradiological correlation, bronchoscopy, and computed tomography-guided biopsy revealed the diagnosis of primary pulmonary non-Hodgkin's lymphoma (PPNHL) on histopathology and immunohistochemistry. We discuss the approach to hilar masses. PPNHL is a rare malignant lymphoma most common being mucosa-associated lymphoid tissue lymphoma. Various therapeutic options are available. The chemotherapy regimen consisting of CHOP (cyclophosphamide, doxorubicin, vincristine, prednisolone) is preferred.
ISSN:	0377-4929 0974-5130
DOI:	10.4103/IJPM.IJPM_71_17